RNA Details
Disease Name
pulmonary fibrosis
Tissue
lung
RNA Symbol
Sav1
RNA ID
299116
RNA Type
mRNA
Alteration Pattern
up regulation
Species
rattus norvegicus
Detection Methods
ELISA; qRT-PCR; Western Blot etc.
Target
NA
Pathway
Hippo signaling pathways
PubMed ID
34536758
Title
Icariin attenuates bleomycin-induced pulmonary fibrosis by targeting Hippo/YAP pathway
Year
2021
Function
"Hippo signaling pathways genes included in this study were Cdh1, Lats1, Fzd2, Gli1, Ctnna1, Sav1, Wnt11, Wnt7a, Wnt3a, Bmp4, Sox2, and Tp73. The fold change of Hippo signaling pathways genes identified that Cdh1, Lats1, Fzd2, Gli1, Ctnna1, Sav1, Wnt11, Wnt7a, Bmp4, and Wnt3a were highly expressed in BLM compared with normal control samples. Sox2 and Tp73 exhibited lower expression in BLM than in normal control groups."